evaluation of serum creatine phosphokinase in diagnosis of tubal ectopic pregnancy compared with intrauterine pregnancy and threatened abortion
نویسندگان
چکیده
background: vaginal sonograghy and serial -hcg are the most common diagnostic methods for ectopic pregnancy but about 50% of cases are initially misdiagnosed. in tubal pregnancy the zygote lies next to the muscular layer, and this invasion causes an increase in creatine phosphokinase (cpk) in blood. objective: assessment of cpk and its isoenzyme cpk-mb as a diagnostic marker for tubal pregnancy. materials and methods: in this case-control study, 111 women between 16-40 years in first-trimester pregnancy admitted to emergency ward of rasht alzahra hospital with abdominal pain or vaginal bleeding were included and according to sonography and βhcg divided into 3 groups (n=37): tubal pregnancy (1), threatened abortion (2) and normal pregnancy (3). blood samples were taken for totalcpk and cpk-mb before any invasive procedure. results: mean total cpk level were 96.27±63.9 u/lit (group 1), 55.37±14.1 u/lit (group 2) and 48.94±19.2 u/lit (group 3) and was significantly higher in tubal pregnancy compared to other groups. mean cpk-mb levels in 3 groups were 15.62±5.2 u/lit, 17.32±6.9 u/lit, and 15.1±4.7 u/lit, respectively which was not significant. conclusion: it seems that determination of total cpk can enhance the diagnostic value of tubal pregnancy.
منابع مشابه
Evaluation of serum creatine phosphokinase in diagnosis of tubal ectopic pregnancy compared with intrauterine pregnancy and threatened abortion
BACKGROUND Vaginal sonograghy and serial -hCG are the most common diagnostic methods for ectopic pregnancy but about 50% of cases are initially misdiagnosed. In tubal pregnancy the zygote lies next to the muscular layer, and this invasion causes an increase in creatine phosphokinase (CPK) in blood. OBJECTIVE assessment of CPK and its isoenzyme CPK-MB as a diagnostic marker for tubal pregnancy...
متن کاملAssessment of The Diagnostic Capability of Serum Creatine Phosphokinase and Its Isoenzyme in Ectopic Pregnancy
متن کامل
Co-existent intrauterine and ectopic tubal pregnancy.
A case of co-existent intrauterine and ectopic pregnancy is described in a patient from overseas. The difficulty in diagnosis and management is discussed, together with recent literature.
متن کاملassessment of the diagnostic capability of serum creatine phosphokinase and its isoenzyme in ectopic pregnancy
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متن کاملAssessment of The Diagnostic Capability of Serum Creatine Phosphokinase and Its Isoenzyme in Ectopic Pregnancy
BACKGROUND Our goal was to assess the diagnostic value of creatine phosphokinase (CPK) and its isoenzyme CPK- muscle brain (MB) in ectopic pregnancy (EP) in order to locate a simpler diagnostic approach for EP. MATERIALS AND METHODS This was a prospective study that performed consecutive sampling for 20 months in two major hospitals in Isfahan, Iran. All pregnant patients in their first trime...
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عنوان ژورنال:
international journal of reproductive biomedicineجلد ۱۰، شماره ۴، صفحات ۳۰۳-۰
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